Basic Information

Gene symbol RHO Synonyms CSNBAD1, OPN2, RP4 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description rhodopsin

GTO ID GTC3785
Trial ID NCT06292650
Disease Retinitis Pigmentosa
Altered gene RHO
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment ZM-02
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleProspective, Dose-Escalating, Investigator Initiated Trial to Evaluate the Safety and Efficacy of ZM-02 in Retinitis Pigmentosa
Year2024
CountryChina
Company sponsorZhongmou Therapeutics
Other ID(s)ZM-02
Vector information
Vectoradeno-associated virus
Vector typeadeno-associated virus (AAV) vector
Transgene/Inserted geneRHO gene

Clinical Result

Cohort 1
Administration route intravitreal injection
Pts 12
Age Adult, Older_Adult

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