Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3777
Trial ID NCT06285422
Disease Non-Hodgkin's Lymphoma | Large B-Cell Lymphoma
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment SC262
PhasePhase1
Recruitment statusRecruiting
TitleA Phase 1 Study Evaluating SC262, a Hypoimmune, Allogeneic CD22-directed CAR T Cell Therapy, in Relapsed and/or Refractory Non-Hodgkin's Lymphoma (VIVID)
Year2024
CountryUnited States
Company sponsorSana Biotechnology
Other ID(s)SC262-101

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Allogeneic
Pts 35
Age Adult, Older_Adult
Lymph depletion Yes

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