Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3776
Trial ID NCT06285279
Disease Lupus Nephritis | Vasculitis | Membranous Nephropathy
Altered gene BCMA|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment FKC288
PhasePhase1
Recruitment statusRecruiting
TitleEvaluation of the Safety and Efficacy of FKC288 in Participants With Autoimmune Kidney Diseases: A Single-center Exploratory Clinical Study
Year2024
CountryChina
Company sponsorNanjing University School of Medicine
Other ID(s)NJCT-2401
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.1E6 cells/kg, 0.3E6 cells/kg, 1.0E6 cells/kg, 3.0E6 cells/kg
Donor type autologous
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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