Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol TNFSF13B Synonyms BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4 Type of gene protein-coding
Description TNF superfamily member 13b

GTO ID GTC3771
Trial ID NCT06279923
Disease Systemic Lupus Erythematosus | Immune Nephritis | Systemic Sclerosis | Dermatomyositis | Neuromyelitis Optica
Altered gene CD19|TNFSF13B
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BAFF/CD19 CAR-T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleClinical Study of Targeting CD19-BAFF CAR-T Cells in the Treatment of Autoimmune Diseases
Year2024
CountryChina
Company sponsorZhejiang University
Other ID(s)TXB2023023

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 45
Age Adult, Older_Adult

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