Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC3768
Trial ID NCT06277427
Disease Lupus Nephritis
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PRG-1801|BCMA CAR-T cells
PhaseNot Applicable
Recruitment statusRecruiting
TitleRefractory ANCA Associated Vasculitis and Lupus Nephritis Treated With BCMA-targeting CAR-T Cells
Year2024
CountryChina
Company sponsorLingli Dong
Other ID(s)[2023]S208

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2.5E6cells/kg, 5.0E6 cells/kg
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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