Basic Information

Gene symbol STEAP2 Synonyms IPCA1, PCANAP1, PUMPCn, STAMP1, STMP Type of gene protein-coding
Description STEAP2 metalloreductase

GTO ID GTC3761
Trial ID NCT06267729
Disease Prostate Cancer
Altered gene STEAP2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment AZD0754
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Phase I/II Open Label Study to Evaluate the Safety, Cellular Kinetics, and Efficacy of AZD0754, a Chimeric Antigen Receptor (CAR) T-cell Therapy Directed Against STEAP2, in Adult Participants With Metastatic Prostate Cancer: APOLLO
Year2024
CountryAustralia|United States
Company sponsorAstraZeneca
Other ID(s)D9660C00001

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 60
Age Adult, Older_Adult

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