Gene symbol | STEAP2 | Synonyms | IPCA1, PCANAP1, PUMPCn, STAMP1, STMP | Type of gene | protein-coding |
Chromosome | 7 | Map location | 7q21.13 | dbXrefs | |
Description | STEAP2 metalloreductase |
GTO ID | GTC3761 |
Trial ID | NCT06267729 |
Disease | Prostate Cancer |
Altered gene | STEAP2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | AZD0754 |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | A Phase I/II Open Label Study to Evaluate the Safety, Cellular Kinetics, and Efficacy of AZD0754, a Chimeric Antigen Receptor (CAR) T-cell Therapy Directed Against STEAP2, in Adult Participants With Metastatic Prostate Cancer: APOLLO |
Year | 2024 |
Country | Australia|United States |
Company sponsor | AstraZeneca |
Other ID(s) | D9660C00001 |
Cohort 1 | |||||||||
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