Basic Information

Gene symbol MSLN Synonyms MPF, SMRP Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mesothelin

GTO ID GTC3759
Trial ID NCT06256055
Disease Malignant Mesothelioma | Colorectal Cancer | Bile Duct Cancer | Rectal Cancer | Ovary Cancer | Pancreatic Cancer | Breast Cancer Female
Altered gene MSLN
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment UCMYM802
PhasePhase1
Recruitment statusRecruiting
TitleA First-In-Human, Single Arm, Open-label, Phase 1 Dose-Escalation Study of UCMYM802 Injection in Mesothelin-positive Advanced Malignant Solid Tumors
Year2024
CountryChina
Company sponsorUTC Therapeutics Inc.
Other ID(s)UCMYM802-Ⅰ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E8~2E9 cells
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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