Basic Information

Gene symbol ERBB2 Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description erb-b2 receptor tyrosine kinase 2

GTO ID GTC3757
Trial ID NCT06254807
Disease Solid Tumor
Altered gene HER2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CT-0525
PhasePhase1
Recruitment statusRecruiting
TitleAn Open-Label, Single-Arm Study of Autologous Anti-HER2 Chimeric Antigen Receptor Monocytes (CT-0525), in Participants With HER2 Over Expressing Solid Tumors
Year2024
CountryUnited States
Company sponsorCarisma Therapeutics Inc
Other ID(s)Study 102

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 3E10~1E11 cells
Donor type autologous
Pts 6
Age Adult, Older_Adult

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