Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3756
Trial ID NCT06253663
Disease Mantle Cell Lymphoma | B-Precursor Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KTE-X19|Tecartus|Brexucabtagene autoleucel
Location approved US, EU, UK, Australia, Canada
PhasePhase2
Recruitment statusRecruiting
TitleA Phase 2 Multicenter Study Evaluating the Safety and the Efficacy of KTE-X19 in Adult Japanese Subjects With Relapsed/Refractory Mantle Cell Lymphoma or Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia
Year2024
CountryJapan
Company sponsorKite, A Gilead Company
Other ID(s)KT-US-472-0149

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6~E8 cells/kg, 2E6~E8 cells/kg
Pts 21
Age Adult, Older_Adult
Lymph depletion Yes

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