Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC3751
Trial ID NCT06249438
Disease Systemic Lupus Erythematosus | Immune-Mediated Necrotizing Myopathy | Neuromyelitis Optica Spectrum Disorder
Altered gene CD20|BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment C-CAR168
PhasePhase1
Recruitment statusRecruiting
TitleAn Exploratory Clinical Study of Anti-B-cell Maturation Antigen(BCMA)/Cluster of Differentiation Antigen 20(CD20) Chimeric Antigen Receptor Autologous T Cell Product (C-CAR168) in the Treatment of Autoimmune Diseases Refractory to Standard Therapy
Year2024
CountryChina
Company sponsorRenJi Hospital
Other ID(s)1141-043(CAR-AID)

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 30
Age Adult, Older_Adult

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