Gene symbol | TNFRSF17 | Synonyms | BCM, BCMA, CD269, TNFRSF13A | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.13 | dbXrefs | |
Description | TNF receptor superfamily member 17 |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC3751 |
Trial ID | NCT06249438 |
Disease | Systemic Lupus Erythematosus | Immune-Mediated Necrotizing Myopathy | Neuromyelitis Optica Spectrum Disorder |
Altered gene | CD20|BCMA |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | C-CAR168 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | An Exploratory Clinical Study of Anti-B-cell Maturation Antigen(BCMA)/Cluster of Differentiation Antigen 20(CD20) Chimeric Antigen Receptor Autologous T Cell Product (C-CAR168) in the Treatment of Autoimmune Diseases Refractory to Standard Therapy |
Year | 2024 |
Country | China |
Company sponsor | RenJi Hospital |
Other ID(s) | 1141-043(CAR-AID) |
Cohort 1 | |||||||||
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