Basic Information

Gene symbol MSLN Synonyms MPF, SMRP Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mesothelin

GTO ID GTC3750
Trial ID NCT06249256
Disease Solid Tumor
Altered gene MSLN
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BZT2312|Fast CAR T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleAn Exploratory Study on the Treatment of Advanced Solid Tumors by Secretory PD1 Nanoantibody Targeting Mesothelin Fast CAR T Cells
Year2023
CountryChina
Company sponsorShanghai Cell Therapy Group Co.,Ltd
Other ID(s)BZT2312-A-01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5E5 cells/kg, 1E6 cells/kg, 5E6 cells/kg
Donor type autologous
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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