Basic Information

Gene symbol MSLN Synonyms MPF, SMRP Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mesothelin

GTO ID GTC3749
Trial ID NCT06248697
Disease Solid Tumor
Altered gene MSLN
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment αPD1/CTLA4-MSLN-CAR T cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleExploratory Study of MSLN-CAR T Cells Secreting PD1/CTLA-4 Nanoantibody for the Treatment of Advanced Solid Tumors
Year2023
CountryChina
Company sponsorShanghai Cell Therapy Group Co.,Ltd
Other ID(s)BZE2209-A-01

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 16
Age Adult, Older_Adult

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