| Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
| Chromosome | 17 | Map location | 17q12 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | erb-b2 receptor tyrosine kinase 2 | ||||
| GTO ID | GTC3744 |
| Trial ID | NCT06241456 |
| Disease | Solid Tumor |
| Altered gene | HER2 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | FT825|ONO-8250 |
| Co-treatment | Bendamustine|DocetaxelCisplatin |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | A Phase 1 Study of FT825/ONO-8250, an Off-the-Shelf CAR T-Cell Therapy, With or Without Monoclonal Antibodies, in HER2-Positive or Other Advanced Solid Tumors |
| Year | 2024 |
| Country | United States |
| Company sponsor | Fate Therapeutics |
| Other ID(s) | FT825-101 |
| Cohort1: CAR-T | |||||||||
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| Cohort2: CAR-T_Cetuximab | |||||||||
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