Basic Information

Gene symbol STEAP1 Synonyms PRSS24, STEAP Type of gene protein-coding
Description STEAP family member 1

GTO ID GTC3740
Trial ID NCT06236139
Disease Castration-Resistant Prostate Carcinoma | Metastatic Prostate Adenocarcinoma | Prostate Cancer
Altered gene STEAP1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment STEAP1 CAR T-cells
Co-treatment Echocardiography
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitlePhase 1/2 Dose-Escalation and Cohort Study of STEAP1 CART With Enzalutamide in Participants With mCRPC
Year2024
CountryUnited States
Company sponsorFred Hutchinson Cancer Center
Other ID(s)RG1123855|NCI-2023-10316|20204

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 48
Age Adult, Older_Adult
Lymph depletion Yes

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