Basic Information

Gene symbol FOLH1 Synonyms FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP Type of gene protein-coding
Description folate hydrolase 1

GTO ID GTC3736
Trial ID NCT06228404
Disease Castration-Resistant Prostate Cancer
Altered gene PSMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PSMA-CAR T
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleThe Safety and Efficacy Evaluation of Enhanced Autologous PSMA Chimeric Antigen Receptor T Cells in the Treatment of Refractory Castration Resistant Prostate Cancer
Year2024
CountryChina
Company sponsorShanghai Changzheng Hospital
Other ID(s)2022-BRL-501

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.25E6 cells/kg of body weight, 0.75E6 cells/kg of body weight, 2E6 cells/kg of body weight
Donor type autologous
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph