Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | erb-b2 receptor tyrosine kinase 2 |
GTO ID | GTC3734 |
Trial ID | NCT06224738 |
Disease | Gastric Cancer |
Altered gene | HER2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-M cell |
Treatment | HER2 CAR-M cell |
Phase | Early_Phase1 |
Recruitment status | Not Recruiting |
Title | Human HER2-targeted Chimeric Antigen Receptor Macrophages Therapy for HER2-positive Advanced Gastric Cancer With Peritoneal Metastases: an Exploratory Clinical Trial |
Year | 2024 |
Country | China |
Company sponsor | First People's Hospital of Hangzhou |
Other ID(s) | ITT-20231107-0257-02 |
Vector information | |||||||||
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Cohort 1 | |||||||||||
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