Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule

GTO ID GTC3730
Trial ID NCT06221553
Disease Diffuse Intrinsic Pontine Glioma
Altered gene CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment B7H3 CAR T cells
PhasePhase1
Recruitment statusRecruiting
TitleSafety and Efficacy of Intraventricular Infusion of B7H3 With IL-7 Receptor Alpha Signaling Chimeric Antigen Receptor T Cell in Diffuse Intrinsic Pontine Glioma
Year2024
CountryThailand
Company sponsorChulalongkorn University
Other ID(s)LV-B7H3IL7-CART-DPG-P1-2023|Chulalongkorn University

Clinical Result

Cohort 1
Administration route intraventricular infusion
Dosage 1E7 cells, 3E7 cells, 1E8 cells
Donor type autologous
Pts 9
Age Child, Adult

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