Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC3725
Trial ID NCT06215950
Disease Ovarian Cancer | Cervix Cancer | Advanced Cancer | Gynecologic Cancer
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD70 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleA Phase I Clinical Study to Assess the Safety and Efficacy of CD70-targeted CAR-T in the Treatment of CD70-positive Advanced/Metastatic Gynecologic Cancer
Year2024
CountryChina
Company sponsorChongqing Precision Biotech Co., Ltd
Other ID(s)PBC061

Clinical Result

Cohort 1
Administration route intravenous infusion|intraperitoneal injection
Dosage 1~10E6 cells/kg
Pts 36
Age Adult, Older_Adult
Lymph depletion Yes

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