Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3724
Trial ID NCT06213636
Disease Acute Lymphoblastic Leukemia | B-Cell Non-Hodgkin's Lymphoma | Diffuse Large B Cell Lymphoma | Central Nervous System Lymphoma | Follicular Lymphoma | Mantle Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells|EB-BH2024
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleT-cell Infusion Targeting CD19 and CD22 for Refractory/Relapsed Leukemia/Lymphoma Patients With or Without Central Nervous System Involvement
Year2024
CountryChina
Company sponsorEssen Biotech
Other ID(s)ESBI202491

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 75
Age Child, Adult, Older_Adult
Lymph depletion Yes

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