Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3718
Trial ID NCT06208735
Disease B-Cell Leukemia | Non-Hodgkin's Lymphoma | Diffuse Large B Cell Lymphoma | High-Grade B-Cell Lymphoma | Primary Mediastinal Large B-Cell Lymphoma | Mantle Cell Lymphoma | B-Cell Lymphoma
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CLIC-2201
PhasePhase1
Recruitment statusNot Recruiting
TitleCLIC-02: A Phase I Trial of CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
Year2024
CountryCanada
Company sponsorBritish Columbia Cancer Agency
Other ID(s)CLIC-02

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 24
Age Child, Adult, Older_Adult
Lymph depletion Yes

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