Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

GTO ID GTC3715
Trial ID NCT06201247
Disease Acute Myeloid Leukemia
Altered gene CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment JD123
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleSafety and Efficacy of Universal Off-the-shelf CAR-NK Cells Targeted CD123 (JD123 Injection) in the Treatment of Refractory or Relapsed CD123-positive Acute Myeloid Leukemia
Year2023
CountryChina
Company sponsorPeking University People's Hospital
Other ID(s)2023PHD016-001

Clinical Result

Cohort 1
Administration route infusion
Dosage 5.0E8 cells/dose, 1.5E9 cells/dose, 3.0E9 cells/dose
Donor type Allogeneic
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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