| Gene symbol | GPC3 | Synonyms | DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 | Type of gene | protein-coding | |
| Chromosome | X | Map location | Xq26.2 | dbXrefs | Entrez:2719 MIM:300037 HGNC:HGNC:4451 Ensembl:ENSG00000147257 AllianceGenome:HGNC:4451 | |
| Description | glypican 3 | |||||
| GTO ID | GTC3712 |
| Trial ID | NCT06198296 |
| Disease | Hepatoblastoma | Hepatocellular Carcinoma | Wilms' Tumor | Malignant Rhabdoid Tumor | Yolk Sac Tumor | Rhabdomyosarcoma | Liposarcoma | Embryonal Sarcoma of Liver |
| Altered gene | GPC3 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | 21.15.GPC3-CAR T cells |
| Phase | Phase1 |
| Recruitment status | Not Recruiting |
| Title | Immunotherapy For Adults With GPC3-Positive Solid Tumors Using Interleukin-15 And -21 Armored Glypican-3-Specific Chimeric Antigen Receptor Expressing Autologous T Cells |
| Year | 2023 |
| Country | United States |
| Company sponsor | Baylor College of Medicine |
| Other ID(s) | H-54859 Co-EXIST |
| Cohort 1 | |||||||||||||
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