Basic Information

Gene symbol GUCY2C Synonyms DIAR6, GC-C, GCC, GUC2C, HSER, MECIL, MUCIL, STAR Type of gene protein-coding
Description guanylate cyclase 2C

GTO ID GTC3710
Trial ID NCT06197178
Disease Gastrointestinal Tumor
Altered gene GCC
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment LCAR-G08
PhasePhase1
Recruitment statusRecruiting
TitleA Phase 1, Open-Label Study Evaluating the Safety, Tolerability and Efficacy of (LCAR)-G08, a Chimeric Antigen Receptor (CAR)-T Cell Therapy Targeting Guanylyl Cyclase C (GCC) in Subjects With Advanced Gastrointestinal Tumors
Year2024
CountryChina
Company sponsorPeking University
Other ID(s)LB2301-0001

Clinical Result

Cohort 1
Administration route infusion
Pts 42
Age Adult, Older_Adult
Lymph depletion Yes

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