Gene symbol | GUCY2C | Synonyms | DIAR6, GC-C, GCC, GUC2C, HSER, MECIL, MUCIL, STAR | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p12.3 | dbXrefs | |
Description | guanylate cyclase 2C |
GTO ID | GTC3710 |
Trial ID | NCT06197178 |
Disease | Gastrointestinal Tumor |
Altered gene | GCC |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | LCAR-G08 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase 1, Open-Label Study Evaluating the Safety, Tolerability and Efficacy of (LCAR)-G08, a Chimeric Antigen Receptor (CAR)-T Cell Therapy Targeting Guanylyl Cyclase C (GCC) in Subjects With Advanced Gastrointestinal Tumors |
Year | 2024 |
Country | China |
Company sponsor | Peking University |
Other ID(s) | LB2301-0001 |
Cohort 1 | |||||||||
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