Basic Information

Gene symbol PSCA Synonyms PRO232, lncPSCA Type of gene protein-coding
Description prostate stem cell antigen

GTO ID GTC3703
Trial ID NCT06193486
Disease Prostate Cancer
Altered gene PSCA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment MSGV1-PSCA-8T28Z
PhasePhase1
Recruitment statusRecruiting
TitleA Phase I Clinical Trial of an Infusion of Autologous Gamma Delta T Cells Genetically Engineered With a Chimeric Receptor to Target the Prostate Stem Cell Antigen in Patients With Metastatic Castration Resistant Prostate Cancer
Year2024
CountryUnited States
Company sponsorH. Lee Moffitt Cancer Center and Research Institute
Other ID(s)MCC-22344

Clinical Result

Cohort 1
Administration route infusion
Dosage 1E5 cells/kg, 3E5 cells/kg, 1E6 cells/kg, 3E6 cells/kg, 1E6 cells/kg
Donor type autologous
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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