Gene symbol | EPHA2 | Synonyms | ARCC2, CTPA, CTPP1, CTRCT6, ECK | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1p36.13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | EPH receptor A2 |
Gene symbol | IL13RA2 | Synonyms | CD213A2, CT19, IL-13R, IL13BP | Type of gene | protein-coding |
Chromosome | X | Map location | Xq23 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | interleukin 13 receptor subunit alpha 2 |
GTO ID | GTC3699 |
Trial ID | NCT06186401 |
Disease | Glioblastoma |
Altered gene | EPHA2|IL13RA2 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | E-SYNC T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Phase 1 Study of Autologous Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13R alpha2 CAR (E-SYNC) T Cells in Adult Participants With EGFRvIII+ Glioblastoma |
Year | 2024 |
Country | United States |
Company sponsor | Hideho Okada, MD, PhD |
Other ID(s) | 23704|5U19CA264338-03 |
Cohort 1 | |||||||||||||
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