Basic Information

Gene symbol TNFRSF8 Synonyms CD30, D1S166E, Ki-1 Type of gene protein-coding
Description TNF receptor superfamily member 8

GTO ID GTC3692
Trial ID NCT06176690
Disease Diffuse Large B-Cell Lymphoma | Anaplastic Large Cell Lymphoma | T-Cell Lymphoma | Non-Hodgkin's Lymphoma | Hodgkin's Lymphoma
Altered gene CD30
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment C7R.CD30.CAR-EBVST cells
PhasePhase1
Recruitment statusNot Recruiting
TitleConstitutive IL7R (C7R) Modified Banked Allogeneic CD30 Chimeric Antigen Receptor Epstein-Barr Virus-Specific T Lymphocytes (CD30.CAR-EBVSTs) in Patients With Relapsed or Refractory CD30-Positive Lymphomas
Year2024
CountryUnited States
Company sponsorBaylor College of Medicine
Other ID(s)H-54063, CABAL

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 4E7 cells, 1E8 cells, 4E8 cells, 8E8 cells
Donor type autologous
Pts 90
Age Child, Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph