Basic Information

Gene symbol CD86 Synonyms B7-2, B7.2, B70, CD28LG2, LAB72 Type of gene protein-coding
Description CD86 molecule

Gene symbol PDCD1 Synonyms CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description programmed cell death 1

GTO ID GTC3690
Trial ID NCT06171282
Disease Osteosarcoma | Soft Tissue Sarcoma | Bone Tumor
Altered gene CD86|PDCD1
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment R130
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleA Clinical Safety and Efficacy Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue Tumors
Year2023
CountryChina
Company sponsorShanghai Yunying Medical Technology
Other ID(s)SHYY-R130-BSTT
Vector information
Vectorherpes simplex virus

Clinical Result

Cohort 1
Administration route intratumoral injection
Dosage 1E8 PFU/mL
Pts 9
Age Child, Adult, Older_Adult

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