Gene symbol | MAGEA4 | Synonyms | CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B | Type of gene | protein-coding |
Chromosome | X | Map location | Xq28 | dbXrefs | |
Description | MAGE family member A4 |
GTO ID | GTC3689 |
Trial ID | NCT06170294 |
Disease | Advanced Solid Tumor |
Altered gene | MAGE-A4 |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | MAGE-A4 TCR-T cells |
HLA | HLA-A*02 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Single-arm, Open-label, Dose Exploratory Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Autologous Humanized MAGE-A4-directed T Cell Receptor Engineered T Cell (JWTCR001) in Patients With Advanced Solid Tumors |
Year | 2023 |
Country | China |
Company sponsor | Peking University |
Other ID(s) | JWTCR001001 |
Cohort 1 | |||||||||||
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