Basic Information

Gene symbol MAGEA4 Synonyms CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B Type of gene protein-coding
Description MAGE family member A4

GTO ID GTC3689
Trial ID NCT06170294
Disease Advanced Solid Tumor
Altered gene MAGE-A4
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment MAGE-A4 TCR-T cells
HLAHLA-A*02
PhasePhase1
Recruitment statusRecruiting
TitleA Single-arm, Open-label, Dose Exploratory Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Autologous Humanized MAGE-A4-directed T Cell Receptor Engineered T Cell (JWTCR001) in Patients With Advanced Solid Tumors
Year2023
CountryChina
Company sponsorPeking University
Other ID(s)JWTCR001001

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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