| Gene symbol | PCSK9 | Synonyms | FH3, FHCL3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9 | Type of gene | protein-coding |
| Chromosome | 1 | Map location | 1p32.3 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | proprotein convertase subtilisin/kexin type 9 | ||||
| GTO ID | GTC3687 |
| Trial ID | NCT06164730 |
| Disease | Heterozygous Familial Hypercholesterolemia | Premature Coronary Heart Disease |
| Altered gene | PCSK9 |
| Therapeutic/Target gene | Target gene |
| Therapy | Gene editing |
| Treatment | VERVE-102 |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | Open-label, Phase 1b, Single Ascending Dose Study to Evaluate the Safety of VERVE-102 Administered to Patients With Heterozygous Familial Hypercholesterolemia or Premature Coronary Artery Disease Who Require Additional Lowering of Low-density Lipoprotein Cholesterol |
| Year | 2023 |
| Country | Canada|United Kingdom |
| Company sponsor | Verve Therapeutics, Inc. |
| Other ID(s) | VT-10201 |
| Vector information | |||
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| Cohort 1 | |||||||
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