| Gene symbol | CD276 | Synonyms | 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 | Type of gene | protein-coding |
| Chromosome | 15 | Map location | 15q24.1 | dbXrefs | |
| Description | CD276 molecule | ||||
| GTO ID | GTC3686 |
| Trial ID | NCT06158139 |
| Disease | Pancreas Cancer |
| Altered gene | CD276 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | iC9-CAR.B7-H3 T cells |
| Phase | Phase1 |
| Recruitment status | Not Recruiting |
| Title | A Phase I Study of Autologous CAR-T Cells Targeting the B7-H3 Antigen and Containing the Inducible Caspase 9 Safety Switch in Subjects With Refractory Pancreatic Ductal Adenocarcinoma (PDAC) |
| Year | 2024 |
| Country | United States |
| Company sponsor | UNC Lineberger Comprehensive Cancer Center |
| Other ID(s) | LCCC2223-ATL |
| Cohort 1 | |||||||||
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