Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3684
Trial ID NCT06154252
Disease Idiopathic Inflammatory Myopathy | Dermatomyositis | Anti-Synthetase Syndrome | Immune-Mediated Necrotizing Myopathy
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CABA-201
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Phase 1/2, Open-Label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T Cells (CABA-201) in Subjects With Active Idiopathic Inflammatory Myopathy
Year2023
CountryUnited States
Company sponsorCabaletta Bio
Other ID(s)CAB-201-002

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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