Gene symbol | TNFRSF17 | Synonyms | BCM, BCMA, CD269, TNFRSF13A | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.13 | dbXrefs | |
Description | TNF receptor superfamily member 17 |
Gene symbol | GPRC5D | Synonyms | None | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | G protein-coupled receptor class C group 5 member D |
GTO ID | GTC3683 |
Trial ID | NCT06153251 |
Disease | Multiple Myeloma |
Altered gene | BCMA|GPRC5D |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | BMS-986453 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase 1, Open-Label, Dose-Finding Study of BMS-986453, Dual Targeting BCMAxGPRC5D Chimeric Antigen Receptor T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma |
Year | 2024 |
Country | France|Germany|Spain|United States |
Company sponsor | Juno Therapeutics, Inc., a Bristol-Myers Squibb Company |
Other ID(s) | CA119-0002 |
Cohort 1 | |||||||||
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