Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol GPRC5D Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description G protein-coupled receptor class C group 5 member D

GTO ID GTC3683
Trial ID NCT06153251
Disease Multiple Myeloma
Altered gene BCMA|GPRC5D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BMS-986453
PhasePhase1
Recruitment statusRecruiting
TitleA Phase 1, Open-Label, Dose-Finding Study of BMS-986453, Dual Targeting BCMAxGPRC5D Chimeric Antigen Receptor T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma
Year2024
CountryFrance|Germany|Spain|United States
Company sponsorJuno Therapeutics, Inc., a Bristol-Myers Squibb Company
Other ID(s)CA119-0002

Clinical Result

Cohort 1
Administration route None
Pts 130
Age Adult, Older_Adult
Lymph depletion Yes

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