Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3682
Trial ID NCT06153095
Disease Systemic Lupus Erythematosus | Lupus Nephritis
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment IMPT-514
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Phase 1/2 Open-label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of IMPT-514 in Participants With Active, Refractory Lupus Nephritis and Systemic Lupus Erythematosus
Year2024
CountryAustralia|United States
Company sponsorImmPACT Bio
Other ID(s)MPCT-021N

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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