Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3673
Trial ID NCT06144606
Disease B-Cell Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KTE-X19|Tecartus|Brexucabtagene autoleucel
Location approved US, EU, UK, Australia, Canada
PhasePhase2
Recruitment statusRecruiting
TitlePhase 2 Study of KTE-X19 in Minimal Residual Disease (MRD) Positive B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Year2023
CountryUnited States
Company sponsorH. Lee Moffitt Cancer Center and Research Institute
Other ID(s)MCC-22286
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route infusion
Dosage 1E6 cells/kg, 1E8 cells/kg
Donor type autologous
Pts 60
Age Adult, Older_Adult

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