Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC3672
Trial ID NCT06144385
Disease Liver Carcinoma
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment JWCAR204|CAR-GPC3 T cells
PhasePhase1
Recruitment statusRecruiting
TitleA Phase 1, Single-arm, Open-label, Dose-escalation Study of JWATM204 as T Cell-targeted Immunotherapy in the Treatment Amongst Subjects With Advanced Hepatocellular Carcinoma
Year2022
CountryChina
Company sponsorShanghai Ming Ju Biotechnology Co., Ltd.
Other ID(s)JWATM204001

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E8 cells, 3E8 cells, 1E9 cells, 3E9 cells
Donor type autologous
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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