Basic Information

Gene symbol F Synonyms None Type of gene protein-coding
Description Fusion protein (F)

GTO ID GTC3671
Trial ID NCT06143046
Disease Respiratory Syncytial Virus Infectious Disease
Altered gene F
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment mRNA-1345
PhasePhase2
Recruitment statusRecruiting
TitleA Phase 2, Randomized, Observer-Blind, Placebo-Controlled, Dose-Escalation Study to Evaluate the Reactogenicity, Safety, and Immunogenicity of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, in Pregnant Women, and Safety and Immunogenicity in Infants Born to Vaccinated Mothers
Year2023
CountryCanada|Chile|Denmark|Japan|Panama|South Africa|United Kingdom|United States
Company sponsorModernaTX, Inc.
Other ID(s)mRNA-1345-P201|2023-505359-37-00
Vector information
Vectorlipid nanoparticle

Clinical Result

Cohort1: mRNA-1345
Administration route intramuscular injection
Dosage mRNA-1345, Dose A, B, C, single injection of each dose, period from 28 weeks to 36 weeks of gestation
Age Adult
Cohort2: Placebo
Administration route intramuscular injection
Dosage placebo, single injection, period from 28 weeks to 36 weeks of gestation
Age Adult

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