Gene symbol | GH1 | Synonyms | GH, GH-N, GHB5, GHN, IGHD1A, IGHD1B, IGHD2, hGH-N | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q23.3 | dbXrefs | |
Description | growth hormone 1 |
Gene symbol | LIPF | Synonyms | GL, HGL, HLAL | Type of gene | protein-coding |
Chromosome | 10 | Map location | 10q23.31 | dbXrefs | |
Description | lipase F, gastric type |
Gene symbol | UL128 | Synonyms | None | Type of gene | protein-coding |
Chromosome | - | Map location | NC_006273.2 | dbXrefs | |
Description | contains signal peptide; similar to CC chemokines; complexed with envelope glycoproteins H and L; essential in non-fibroblast cells; involved in cell entry |
Gene symbol | UL130 | Synonyms | None | Type of gene | protein-coding |
Chromosome | - | Map location | NC_006273.2 (176984..177628, complement) | dbXrefs | |
Description | envelope glycoprotein UL130 |
Gene symbol | UL131A | Synonyms | None | Type of gene | protein-coding |
Chromosome | - | Map location | NC_006273.2 (177649..178146, complement) | dbXrefs | |
Description | envelope protein UL131A |
GTO ID | GTC3662 |
Trial ID | NCT06133010 |
Disease | Human Cytomegalovirus Infection |
Altered gene | gB|gH|gL|UL128|UL130|UL131A |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | mRNA-1647 |
Phase | Phase2 |
Recruitment status | Withdrawn |
Title | A Phase 2, Observer-Blind, Placebo-Controlled, Proof-of-Concept Trial to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus Vaccine in Liver Transplant Candidates and Recipients |
Year | 2024 |
Country | United States |
Company sponsor | ModernaTX, Inc. |
Other ID(s) | mRNA-1647-P206 |
Vector information | |||
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Cohort1: mRNA-1647 | |||||||||
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Cohort2: Placebo | |||||||||
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