Basic Information

Gene symbol TNFSF13 Synonyms APRIL, CD256, TALL-2, TALL2, TNLG7B, TRDL-1, UNQ383/PRO715, ZTNF2 Type of gene protein-coding
Description TNF superfamily member 13

Gene symbol TNFSF13B Synonyms BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNLG7A, ZTNF4 Type of gene protein-coding
Description TNF superfamily member 13b

GTO ID GTC3661
Trial ID NCT06132711
Disease Multiple Myeloma
Altered gene TNFSF13|TNFSF13B
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment APRIL-BAFF-Bicephali CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleSafety and Efficacy of APRIL-BAFF-Bicephali CAR-T in Relapsed, Refractory Multiple Myeloma-A Single-center, Open-label, Single-arm Clinical Study
Year2023
CountryChina
Company sponsorXuzhou Medical University
Other ID(s)XYFY2023-KL144-01
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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