Basic Information

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC3660
Trial ID NCT06128044
Disease Acute Myeloid Leukemia
Altered gene CLL1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CB-012
PhasePhase1
Recruitment statusRecruiting
TitleA Phase 1, Multicenter, Open-Label Study of CB-012, a CRISPR-Edited Allogeneic Anti-CLL-1 CAR-T Cell Therapy in Patients With Relapsed/Refractory Acute Myeloid Leukemia
Year2024
CountryUnited States
Company sponsorCaribou Biosciences, Inc.
Other ID(s)CB12A

Clinical Result

Cohort 1
Administration route None
Donor type Allogeneic
Pts 70
Age Adult, Older_Adult
Lymph depletion Yes

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