Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol HAVCR2 Synonyms CD366, HAVcr-2, KIM-3, SPTCL, TIM3, TIMD-3, TIMD3, Tim-3 Type of gene protein-coding
Description hepatitis A virus cellular receptor 2

GTO ID GTC3657
Trial ID NCT06125652
Disease Acute Myeloid Leukemia
Altered gene HAVCR2|CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Tim-3/CD123 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleApplication of Anti Tim-3/CD123 CAR-T Cell Therapy in Relapsed and Refractory Acute Myeloid Leukemia (rr/AML)
Year2023
CountryChina
Company sponsorXuzhou Medical University
Other ID(s)XYFY2023-KL358-01

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 20
Age Adult, Older_Adult

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