Basic Information

Gene symbol GPRC5D Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description G protein-coupled receptor class C group 5 member D

GTO ID GTC3656
Trial ID NCT06121843
Disease Multiple Myeloma
Altered gene GPRC5D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BMS-986393|CC-95266
Co-treatment Alnuctamab
PhasePhase1
Recruitment statusRecruiting
TitleA Phase 1, Multicenter, Open-label Study to Evaluate the Safety and Preliminary Efficacy of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma and Determine the Recommended Dose for Each Add-on Investigational Component
Year2024
CountryCanada|United States
Company sponsorJuno Therapeutics, Inc., a Bristol-Myers Squibb Company
Other ID(s)CA088-1005

Clinical Result

Cohort1: CAR-T_Alnuctamab
Administration route None
Age Adult, Older_Adult
Cohort2: CAR-T_Mezigdomide
Administration route None
Age Adult, Older_Adult
Cohort3: CAR-T_Iberdomide
Administration route None
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph