Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
GTO ID | GTC3639 |
Trial ID | NCT06102525 |
Disease | Glioblastoma |
Altered gene | TERT |
Therapeutic/Target gene | Target gene|Therapeutic gene |
Therapy | Ribozyme |
Treatment | RZ-001 |
Co-treatment | VGCV |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | A Phase 1/2a, Open-label, Multicenter, Dose Escalation and Dose Expansion Study Evaluating the Safety, Tolerability, and Efficacy of RZ-001 in Combination With Valganciclovir in Subjects With Glioblastoma |
Year | 2023 |
Country | United States |
Company sponsor | Ribozyome |
Other ID(s) | RZ-001-201 |
Vector information | |||||||||
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Cohort1: RZ-001_Dose 1 | |||||||||
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Cohort2: RZ-001_Dose 2 | |||||||||
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Cohort3: RZ-001_Dose 3 | |||||||||
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Cohort4: RZ-001_Dose 4 | |||||||||
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Cohort5: RZ-001_Dose 5 | |||||||||
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Cohort6: RZ-001_Dose 6 | |||||||||
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