Basic Information

Gene symbol ERBB2 Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description erb-b2 receptor tyrosine kinase 2

GTO ID GTC3637
Trial ID NCT06101082
Disease Solid Tumor
Altered gene HER2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment HER2 CAR-T cell
PhasePhase1
Recruitment statusRecruiting
TitleAn Exploratory Clinical Study Evaluating the Safety and Efficacy of Anti-HER2-CAR-T Cells Injection in Patients With HER2+ Locally Advanced and/ or Metastatic Solid Tumors
Year2024
CountryChina
Company sponsorChina Medical University, China
Other ID(s)HER2-CN-A1

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg, 3E6 cells/kg, 1E7 cells/kg
Pts 9
Age Adult, Older_Adult
Lymph depletion Yes

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