Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3634
Trial ID NCT06097455
Disease Non-Hodgkin's Lymphoma
Altered gene BCMA|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ARI0003
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleFirst in Human, Pilot, Open-label, Prospective, Multicentre, Non-randomised Clinical Trial to Evaluate the Safety and Efficacy of ARI0003 (CART CD19/ CD269 Cells) in Patients With Relapsed/Refractory B-cell Aggressive Lymphoma
Year2024
CountrySpain
Company sponsorFundacion Clinic per a la Recerca Biomédica
Other ID(s)CARTD-BG-1|2023-5072-13-97-00
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5~5E6 cell/kg
Pts 40
Age Adult, Older_Adult
Lymph depletion Yes

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