Basic Information

Gene symbol CSPG4 Synonyms CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2 Type of gene protein-coding
Description chondroitin sulfate proteoglycan 4

GTO ID GTC3632
Trial ID NCT06096038
Disease Head and Neck Cancer
Altered gene CSPG4
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment iC9.CAR-CSPG4 T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleAdministration of T Cells Expressing Chondroitin-Sulfate-Proteoglycan-4 Specific Chimeric Antigen Receptors (CAR) in Subjects With Head and Neck Squamous Cell Carcinoma (HNSCC)
Year2024
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC2060-ATL

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 33
Age Adult, Older_Adult
Lymph depletion Yes

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