Basic Information

Gene symbol CCR4 Synonyms CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description C-C motif chemokine receptor 4

Gene symbol TNFRSF8 Synonyms CD30, D1S166E, Ki-1 Type of gene protein-coding
Description TNF receptor superfamily member 8

GTO ID GTC3626
Trial ID NCT06090864
Disease Hodgkin's Lymphoma
Altered gene CD30|CCR4
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ATLCAR.CD30.CCR4 cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleThe Administration of T Lymphocytes Expressing the CD30 Chimeric Antigen Receptor (CAR) and CCR4 for Relapsed/Refractory CD30+ Hodgkin s Lymphoma
Year2024
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC2222-ATL

Clinical Result

Cohort 1
Administration route infusion
Pts 31
Age Adult, Older_Adult
Lymph depletion Yes

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