Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC3624
Trial ID NCT06087341
Disease Sarcoma
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment NKG2D-CAR memory T cell
PhasePhase1
Recruitment statusRecruiting
TitleA Phase I Trial of Memory T Cells Expressing an NKG2D Chimeric Antigen Receptor in Children, Adolescents and Young Adults With Advanced Sarcoma
Year2024
CountrySpain
Company sponsorAntonio Pérez Martínez
Other ID(s)CAR4SAR

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 18
Age Child, Adult

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