Gene symbol | KLRK1 | Synonyms | CD314, D12S2489E, KLR, NKG2-D, NKG2D | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | killer cell lectin like receptor K1 |
GTO ID | GTC3624 |
Trial ID | NCT06087341 |
Disease | Sarcoma |
Altered gene | NKG2D |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | NKG2D-CAR memory T cell |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase I Trial of Memory T Cells Expressing an NKG2D Chimeric Antigen Receptor in Children, Adolescents and Young Adults With Advanced Sarcoma |
Year | 2024 |
Country | Spain |
Company sponsor | Antonio Pérez Martínez |
Other ID(s) | CAR4SAR |
Cohort 1 | |||||||
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