| Gene symbol | CD274 | Synonyms | B7-H, B7H1, PD-L1, PDCD1L1, PDCD1LG1, PDL1, hPD-L1 | Type of gene | protein-coding |
| Chromosome | 9 | Map location | 9p24.1 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | CD274 molecule | ||||
| Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding |
| Chromosome | 3 | Map location | 3q22.3 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | claudin 18 | ||||
| GTO ID | GTC3621 |
| Trial ID | NCT06084286 |
| Disease | Solid Tumor |
| Altered gene | CLDN18|CD274 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | CLDN18.2/PD-L1 CAR-T cells |
| Phase | Phase1 |
| Recruitment status | Not Recruiting |
| Title | A Phase I, Open-label, Single-arm, Dose-escalation and Expansion Study of Specific Dual-targeting CLDN18.2 and PD-L1 CAR-T for Patients With CLDN18.2-positive Advanced Solid Tumors |
| Year | 2023 |
| Country | China |
| Company sponsor | Sichuan University |
| Other ID(s) | MCART-007 |
| Cohort 1 | |||||||||
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