Basic Information

Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC3620
Trial ID NCT06083883
Disease Synovial Sarcoma | Myxoid/Round Cell Liposarcoma
Altered gene NY-ESO-1
Therapeutic/Target gene Target gene
TherapyTCR-NK cell
Treatment NY-ESO-1 TCR/IL-15 NK
HLAHLA-A*02:01|HLA-A*02:05|HLA-A*02:06
PhasePhase1
Recruitment statusSuspended
TitlePhase I/Ib Study of Adoptive NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Reactive Against the NY-ESO-1-specific Cord Blood-derived NK Cells (NY-ESO-1 TCR/IL-15 NK) in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma
Year2023
CountryUnited States
Company sponsorM.D. Anderson Cancer Center
Other ID(s)2023-0289|NCI-2023-08752

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Allogeneic
Pts 44
Age Child, Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph