Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC3618
Trial ID NCT06081478
Disease B-Cell Acute Lymphoblastic Leukemia | B-Cell Lymphoma | Diffuse Large B Cell Lymphoma
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20 CAR-T cells
PhasePhase2
Recruitment statusRecruiting
TitleCD19/CD22 Bispecific CAR-T Cell Therapy for Relapsed/Refractory B-cell Lymphoma or Acute Lymphoblastic Leukemia: a Prospective, Single-arm, Single-center, Phase 2 Clinical Trial
Year2022
CountryChina
Company sponsorBeijing Tongren Hospital
Other ID(s)CAR-T001/TR

Clinical Result

Cohort 1
Administration route infusion
Dosage CD19 CAR-T: 2E6 cells/kg; CD22 CAR: 1E6 cells/kg
Donor type autologous
Pts 100
Age Child, Adult, Older_Adult

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