Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC3618 |
Trial ID | NCT06081478 |
Disease | B-Cell Acute Lymphoblastic Leukemia | B-Cell Lymphoma | Diffuse Large B Cell Lymphoma |
Altered gene | CD19|CD20 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD20 CAR-T cells |
Phase | Phase2 |
Recruitment status | Recruiting |
Title | CD19/CD22 Bispecific CAR-T Cell Therapy for Relapsed/Refractory B-cell Lymphoma or Acute Lymphoblastic Leukemia: a Prospective, Single-arm, Single-center, Phase 2 Clinical Trial |
Year | 2022 |
Country | China |
Company sponsor | Beijing Tongren Hospital |
Other ID(s) | CAR-T001/TR |
Cohort 1 | |||||||||||
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